CATION-TRANSPORT ACROSS BULK LIQUID ORGANIC MEMBRANES WITH OLIGOMERS OF (R)-3-HYDROXYBUTANOIC ACID

被引：38

作者：

BURGER, HM ^{[1
]}

SEEBACH, D ^{[1
]}

机构：

[1] SWISS FED INST TECHNOL, ORGAN CHEM LAB, UNIV STR 16, CH-8092 ZURICH, SWITZERLAND

来源：

HELVETICA CHIMICA ACTA | 1993年 / 76卷 / 07期

关键词：

D O I：

10.1002/hlca.19930760717

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Several oligomeric derivatives 1-5 of (R)-3-hydroxybutanoic acid and a cyclic trimer of (R)-3-hydroxypentanoic acid (6) were used as ionophores to transport potassium picrate across a bulk liquid CH2Cl2 membrane. Using the cyclic trimer 1 and an oligomer mixture of (R)-3-hydroxybutanoic acid, 5 (ca. 28-mer), for the transport. experiments, the alkali-metal ions from Li+ to Cs+ and the alkaline-ear-th-metal ions from Mg2+ to Ba2+ were also shown to be transported through the organic phase. Although a pronounced enhancement of the transport rates was observed in the presence of 3-hydroxyalkanoate oligomers, no special selectivity for one ion was detected. The ionophore properties of the investigated oligomers and oligolides derived from 3-hydroxybutanoic acid are compatible with the alleged role of oligo(3-hydroxybutanoate) (c-PHB; ca. 120-mer)as component of ion channels through cell membranes.

引用

页码：2570 / 2580

页数：11

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