INHIBITION OF CELLULAR IMMUNE REACTIONS IN MICE INFECTED WITH LACTIC DEHYDROGENASE VIRUS

被引：73

作者：

HOWARD, RJ

NOTKINS, AL

MERGENHAGEN, SE

机构：

[1] National Institute of Dental Research, National Institutes of Health, Bethesda

来源：

NATURE | 1969年 / 221卷 / 5183期

关键词：

D O I：

10.1038/221873a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

CERTAIN viral infections affect the immune response of the host to heterogenous antigens. Murine leukaemia viruses, such as Moloney, Friend, Rauscher and Gross passage A virus, inhibit antibody formation1-4. In addition, the passage A virus depresses cellular immunity5. On the other hand, lactic dehydrogenase virus (LDV) enhances humoral antibody formation in mice and prevents the development of immunological tolerance to human gamma globulin6,7. The work described here was undertaken to determine the effect of LDV on two cellular immune reactions - skin allograft rejection and the graft-versus-host reaction8. © 1969 Nature Publishing Group.

引用

页码：873 / +

页数：1

共 22 条

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[9] FACILITATION OF INDUCTION OF TOLERANCE TO ALLOGENEIC TISSUE GRAFTS IN ADULT MICE BY EARLY THYMECTOMY
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[10] CELLULAR IMMUNITY
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