EXAMINATION OF HALLUCINOGEN 2,5-DIMETHOXY-4-METHYLAMPHETAMINE

被引：20

作者：

PHILLIPS, GF

MESLEY, RJ

机构：

[1] Drugs sub-Division, London, SE1, Stamford Street

[2] Physical Methods sub-Division, Laboratory of the Government Chemist, S.E.I, London, Stamford Street

来源：

JOURNAL OF PHARMACY AND PHARMACOLOGY | 1969年 / 21卷 / 01期

关键词：

D O I：

10.1111/j.2042-7158.1969.tb08122.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Physical characteristics are reported for a tablet form of a new hallucinogenic drug previously circulating in the USA under the name “STP”. High resolution mass, nmr, ultraviolet and infrared spectrometric evidence, which identify the extracted base as 2,5‐dimethoxy‐4‐methylamphetamine, and its chromatographic behaviour, are compared with the experimental compound “DOM”. Polymorphic modifications exhibiting distinct solid phase infrared spectra have been studied by X‐ray diffraction and by differential calorimetry. Animal behavioural tests indicate that the psychotomimetic activity of the base is comparable with mescaline but up to 50 times more potent. 1969 Royal Pharmaceutical Society of Great Britain

引用

页码：9 / &

共 10 条

[1]

BELLMAN SW, 1968, J ASSOC OFF ANA CHEM, V51, P164

[2]

BRIMBLECOMBE RW, 1964, PSYCHOPHARMACOLOGIA, V4, P139

[3] A POSSIBLE CORRELATION BETWEEN DRUG-INDUCED HALLUCINATIONS IN MAN AND A BEHAVIOURAL RESPONSE IN MICE [J].