CORRELATION IN THE DISCHARGES OF NEIGHBORING RAT RETINAL GANGLION-CELLS DURING PRENATAL LIFE

被引：219

作者：

MAFFEI, L ^{[1
]}

GALLIRESTA, L ^{[1
]}

机构：

[1] SCUOLA NORMALE SUPER PISA,I-56100 PISA,ITALY

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1990年 / 87卷 / 07期

关键词：

prenatal development; visual system;

D O I：

10.1073/pnas.87.7.2861

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The spontaneous discharges of neighboring retinal ganglion cells were recorded simultaneously in anesthetized prenatal rats between embryonic days 18 and 21. We report here that in the majority of cases the firings of neighboring retinal ganglion cells are strongly correlated during prenatal life. Correlation in the discharges of neighboring cells during development has long been suggested as a way to consolidate synaptic connections with a target cell onto which they converge, a model first proposed by Hebb. Correlation in the activities of neighboring neurons in the retina could be the basis of developmental processes such as refinement of retinotopic maps in the brain and segregation of the inputs from the two eyes.

引用

页码：2861 / 2864

页数：4

共 16 条

[1]

DUBIN MW, 1986, J NEUROSCI, V6, P1021

[2] THE INFLUENCE OF NEURONAL-ACTIVITY ON PATTERNS OF SYNAPTIC CONNECTIONS [J].