SUDDEN-DEATH IN CHILDREN RECEIVING NORPRAMIN - A REVIEW OF 3 REPORTED CASES AND COMMENTARY

被引：118

作者：

RIDDLE, MA

NELSON, JC

KLEINMAN, CS

RASMUSSON, A

LECKMAN, JF

KING, RA

COHEN, DJ

机构：

[1] YALE UNIV,SCH MED,DEPT PEDIAT,NEW HAVEN,CT 06510

[2] YALE UNIV,SCH MED,DEPT PSYCHIAT,NEW HAVEN,CT 06510

[3] YALE UNIV,SCH MED,DEPT PSYCHOL,NEW HAVEN,CT 06510

来源：

JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY | 1991年 / 30卷 / 01期

关键词：

DESIPRAMINE; CHILDREN; SUDDEN DEATH;

D O I：

10.1097/00004583-199101000-00016

中图分类号：

B844 [发展心理学（人类心理学）];

学科分类号：

040202 ;

摘要：

The 1990 "package insert" for Norpramin(R), the Merrell Dow Pharmaceuticals Inc., brand of desipramine, was changed to include the following statement in the Adverse Reactions section, "There has been a report of an 'acute collapse' and 'sudden death' in an eight-year-old (18 kg) male, treated for two years for hyperactivity. There have been additional reports of sudden death in children." The purpose of this commentary is to review what is known about the three reported cases of sudden death and to discuss the implications of these tragedies for children receiving treatment with tricyclic drugs.

引用

页码：104 / 108

页数：5

共 20 条

[1]

ABRAMOWICZ M, 1990, MED LETT DRUGS THER, V32, P53

[2]

AMBROSINI PJ, 1987, PSYCHOPHARMACOLOGY 3, P1247

[3] A DOUBLE-BLIND PLACEBO CONTROLLED-STUDY OF DESIPRAMINE IN THE TREATMENT OF ADD - .2. SERUM DRUG LEVELS AND CARDIOVASCULAR FINDINGS [J].