A PRACTICAL AND STEREOSELECTIVE REDUCTION OF 3-KETO-2-METHYL ESTERS OR 3-KETO-2-METHYL AMIDES INTO ERYTHRO-3-HYDROXY-2-METHYL ESTERS OR ERYTHRO-3-HYDROXY-2-METHYL AMIDES WITH NABH4 CATALYZED BY MNCL2

被引：35

作者：

FUJII, H ^{[1
]}

OSHIMA, K ^{[1
]}

UTIMOTO, K ^{[1
]}

机构：

[1] KYOTO UNIV,FAC ENGN,DEPT IND CHEM,SAKYO KU,KYOTO 606,JAPAN

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 43期

关键词：

D O I：

10.1016/0040-4039(91)80775-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Erythro-3-hydroxy-2-methylpropionates or erythro-3-hydroxy-2-methylpropionamides were prepared with high stereoselectivity by NaBH4 reduction of the corresponding 3-keto esters or 3-keto amides in the presence of a catalytic amount of MnCl2.

引用

页码：6147 / 6150

页数：4

共 4 条

[1] HIGHLY STEREOSELECTIVE REDUCTION OF ALPHA-SUBSTITUTED BETA-KETO AMIDES BY MEANS OF HYDROSILANE/F-AND HYDROSILANE/H+ REAGENT - A PRACTICAL APPROACH TO ALDOLS OF BOTH THREO AND ERYTHRO CONFIGURATIONS
FUJITA, M
HIYAMA, T
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1985, 107 (26) : 8294 - 8296
[2] STEREOSELECTIVE REDUCTION OF BETA-KETO-ESTERS WITH ZINC BOROHYDRIDE - STEREOSELECTIVE SYNTHESIS OF ERYTHRO-3-HYDROXY-2-ALKYLPROPIONATES
NAKATA, T
OISHI, T
[J]. TETRAHEDRON LETTERS, 1980, 21 (17) : 1641 - 1644
[3] AN INTRODUCTION OF CHIRAL CENTERS INTO ACYCLIC SYSTEMS BASED ON STEREOSELECTIVE KETONE REDUCTION
OISHI, T
NAKATA, T
[J]. ACCOUNTS OF CHEMICAL RESEARCH, 1984, 17 (09) : 338 - 344
[4] YAMAGUCHI M, 1983, TETRAHEDRON LETT, V24, P5385

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