INVITRO SUSCEPTIBILITY OF QUINOLONE-RESISTANT CAMPYLOBACTER-JEJUNI TO NEW MACROLIDE ANTIBIOTICS

被引：11

作者：

ENDTZ, HP ^{[1
]}

BROEREN, M ^{[1
]}

MOUTON, RP ^{[1
]}

机构：

[1] UNIV HOSP LEIDEN,DEPT MED MICROBIOL,2300 RC LEIDEN,NETHERLANDS

来源：

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES | 1993年 / 12卷 / 01期

关键词：

D O I：

10.1007/BF01997058

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The MICs of erythromycin and three new macrolide antibiotics were determined for 36 quinolone-susceptible and 106 quinolone-resistant Campylobacter jejuni. The MIC90 values of azithromycin, clarithromycin, roxithromycin and erythromycin were 0.5, 4, 16 and 4 mg/l respectively. No difference was found between macrolide activity against the quinolone-susceptible and the quinolone-resistant strains. Clarithromycin and especially azithromycin might eventually replace erythromycin for the treatment of Campylobacter jejuni infections in view of their pharmacological properties.

引用

页码：48 / 50

页数：3

共 17 条

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