KINETIC-SPECTROPHOTOMETRIC DETERMINATION OF PRIMARY AND SECONDARY-AMINES BY REACTION WITH 1-2-NAPHTHOQUINONE-4-SULFONATE

被引：7

作者：

CABEZA, AS

FALCO, PC

LEGUA, CM

机构：

[1] Departamento de Quimica Analltica, Facultad de Quimica, Universidad de Valencia, Valencia, Doctor Moliner, 50

来源：

ANALYTICAL LETTERS | 1994年 / 27卷 / 06期

关键词：

SODIUM 1,2-NAPHTHOQUINONE 4-SULFONATE; BETA-PHENYLETHYLAMINE; EPHEDRINE; D-AMPHETAMINE; DI-AMPHETAMINE; DEOXYEPHEDRINE; (+)METHAMPHETAMINE; KINETIC-SPECTROPHOTOMETRIC DETERMINATION;

D O I：

10.1080/00032719408000281

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A kinetic-spectrophotometric method for the determination of primary and secondary amines is described. It is based on the coloured reaction of these amines with sodium 1,2 Naphthoquinone 4-sulphonate (NQS) in the presence of a non-ionic surfactant. For each determination the optimum conditions were studied and found to be as follows: pH 10.5, Carbonate-bicarbonate buffer 0.1M, Triton X-100 0.1%, Temperature 45 degrees C, and NQS 6.4x10(-3) M and interval of time 45-180s at wavelength 490 nm. The parameters used for the quantitative determinations are the reaction rate and the increase in the absorbance of the kinetic curves. This procedure has been applied to the determination of ephedrine and amphetamine in pharmaceutical samples.

引用

页码：1095 / 1108

页数：14

共 16 条

[1] [Anonymous], 1980, ANAL CHEM, V52, P2242
[2] Cardone M.J., 1987, ANAL CHEM, V59, P2818
[3] MICRO-DETERMINATION OF STIMULANT-DRUGS IN URINE BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY
ENDO, M
IMAMICHI, H
MORIYASU, M
HASHIMOTO, Y
[J]. JOURNAL OF CHROMATOGRAPHY, 1980, 196 (02): : 334 - 336
[4] FALCO P, FRESENIUS J ANAL CHE
[5] FALCO PC, 1993, IN PRESS ANAL LETT, V27
[6] FOLIN O, 1992, J BIOL CHEM, V51, P377
[7] GUKAN T, 1980, J FAC PHARM ISTANBUL, V16, P73
[8] GURKAN T, 1976, MIKROCHIM ACTA, V1, P165
[9] HASHIMOTO Y, 1978, MIKROCHIM ACTA, V2, P493
[10] LEGUA CM, 1993, IN PRESS ANAL CHIM A

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