THE 3-DIMENSIONAL STRUCTURE OF THE COLICIN-E3 IMMUNITY PROTEIN BY DISTANCE GEOMETRY CALCULATION

被引：10

作者：

YAJIMA, S

MUTO, Y

MORIKAWA, S

NAKAMURA, H

YOKOYAMA, S

MASAKI, H

UOZUMI, T

机构：

[1] UNIV TOKYO, DEPT BIOTECHNOL, YAYOI 1-1-1, BUNKYO KU, TOKYO 113, JAPAN

[2] PROT ENGN RES INST, SUITA, OSAKA 565, JAPAN

[3] UNIV TOKYO, GRAD SCH SCI, DEPT BIOPHYS & BIOCHEM, TOKYO 113, JAPAN

来源：

FEBS LETTERS | 1993年 / 333卷 / 03期

关键词：

NUCLEAR MAGNETIC RESONANCE; COLICIN-E3; DISTANCE GEOMETRY; PROTEIN PROTEIN INTERACTION;

D O I：

10.1016/0014-5793(93)80665-H

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The three-dimensional solution structure of the colicin E3 immunity protein (84 residues) was determined by distance geometry calculations. The hydrophilic side of a four-stranded antiparallel beta-sheet constitutes a part of the surface of the protein, and two loops lie on the hydrophobic side of the sheet. All the three specificity-determining residues, which are included in the center of the beta-sheet, display their side groups on the protein surface.

引用

页码：257 / 260

页数：4

共 21 条

[1] MOLECULAR-STRUCTURE AND IMMUNITY SPECIFICITY OF COLICIN-E6, AN EVOLUTIONARY INTERMEDIATE BETWEEN E-GROUP COLICINS AND CLOACIN-DF13 [J].