KINETICS OF CYANOBOROHYDRIDE REDUCTION OF BOVINE RHODOPSIN

被引：12

作者：

FAGER, RS ^{[1
]}

GENTILCORE, PC ^{[1
]}

ABRAHAMSON, EW ^{[1
]}

机构：

[1] UNIV GUELPH,DEPT CHEM,GUELPH N1G 2W1,ONTARIO,CANADA

来源：

VISION RESEARCH | 1978年 / 18卷 / 04期

关键词：

Bos domesticus; rhodopsin; Schiff's base;

D O I：

10.1016/0042-6989(78)90060-3

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Sodium cyanoborohydride reduces bovine rhodopsin's chromophore. The linear dependence of the kinetics on reductant concentration and the pH and temperature dependence of the reaction are evidence for penetration into the hydrophobic pocket of the native molecule. This supports earlier work indicating a Schiffs base linkage between the retinal chromophore and a lysine in the peptide chain. © 1978.

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页码：483 / 488

页数：6

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