USE OF LIPOSOME-ENCAPSULATED DRUGS IN LEISHMANIASIS

被引：36

作者：

ALVING, CR ^{[1
]}

STECK, EA ^{[1
]}

机构：

[1] WALTER REED ARMY INST RES,DEPT MED CHEM,DIV EXPTL THERAPEUT,WASHINGTON,DC 20012

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1979年 / 4卷 / 08期

关键词：

D O I：

10.1016/0968-0004(79)90404-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Leishmaniasis is a parasitic disease of tropical and subtropical areas, which afflicts probably more than 100 million people. Recent studies show that encapsulating drugs in artificial phospholipid vesicles, called liposomes, can make them more than 700 times effective than unencapsulated drugs [1-4]. © 1979.

引用

页码：N175 / N177

页数：3

共 11 条

[1] THERAPY OF LEISHMANIASIS - SUPERIOR EFFICACIES OF LIPOSOME-ENCAPSULATED DRUGS [J].

ALVING, CR ;

STECK, EA ;

CHAPMAN, WL ;

WAITS, VB ;

HENDRICKS, LD ;

SWARTZ, GM ;

HANSON, WL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1978, 75 (06) :2959-2963

[2] IMPROVED THERAPY OF EXPERIMENTAL LEISHMANIASIS BY USE OF A LIPOSOME-ENCAPSULATED ANTIMONIAL DRUG [J].

ALVING, CR ;

STECK, EA ;

HANSON, WL ;

LOIZEAUX, PS ;

CHAPMAN, WL ;

WAITS, VB .

LIFE SCIENCES, 1978, 22 (12) :1021-1026

[3] USE OF PENTOSTAM LIPOSOMES IN CHEMOTHERAPY OF EXPERIMENTAL LEISHMANIASIS [J].

BLACK, CDV ;

WATSON, GJ .

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 1977, 71 (06) :550-552

[4]

HENDRICKS LC, COMMUNICATION

[5] ANTILEISHMANIAL ACTIVITY OF LEPIDINES [J].

KINNAMON, KE ;

STECK, EA ;

LOIZEAUX, PS ;

HANSON, WL ;

CHAPMAN, WL ;

WAITS, VB .

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1978, 27 (04) :751-757

[6]

LYSENKO AJ, 1971, B WORLD HEALTH ORGAN, V44, P515

[7]

MAINZER F., 1940, TRANS ROY SOC TROP MED AND HYG, V33, P405, DOI 10.1016/S0035-9203(40)90042-6

[8] ANTILEISHMANIAL ACTIVITY OF ANTIMONIALS ENTRAPPED IN LIPOSOMES [J].

NEW, RRC ;

CHANCE, ML ;

THOMAS, SC ;

PETERS, W .

NATURE, 1978, 272 (5648) :55-56

[9]

Steck E A, 1974, Prog Drug Res, V18, P289

[10] NEW ASPECTS OF LIPOSOMES [J].

TYRRELL, DA ;

HEATH, TD ;

COLLEY, CM ;

RYMAN, BE .

BIOCHIMICA ET BIOPHYSICA ACTA, 1976, 457 (3-4) :259-302

← 1 2 →