THE EXISTENCE OF UNIQUE B-STRUCTURES IN POLYNUCLEOTIDES WITH ALTERNATING PURINE-PYRIMIDINE SEQUENCES

被引：6

作者：

LOPRETE, DM ^{[1
]}

HARTMAN, KA ^{[1
]}

机构：

[1] UNIV RHODE ISL,DEPT BIOCHEM & BIOPHYS,KINGSTON,RI 02881

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1991年 / 174卷 / 03期

关键词：

D O I：

10.1016/0006-291X(91)91565-T

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The infrared spectra of the sodium salts of calf-thymus DNA, poly(dA-dC)·poly(dG-dT), poly(dA-dT) and poly(dG-dC) were measured for the samples as highly hydrated, nonoriented gels. The bands from the sugar-phosphate vibrational modes show that poly(dG-dC) assumes a B-family structure which is different from the B structures of the other samples. Poly(dG-dC) most likely assumes a wrinkled B structure. The other samples retain a smooth B structure. An alternating purine-pyrimidine sequence is not a sufficient condition for the formation of wrinkled B structure in a polynucleotide. © 1991.

引用

页码：1313 / 1317

页数：5

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