ENZYMATIC-SYNTHESIS OF BICYCLIC GAMMA-LACTAMS USING CLAVAMINIC ACID SYNTHASE

被引:14
作者
BALDWIN, JE
ADLINGTON, RM
BRYANS, JS
LLOYD, MD
SEWELL, TJ
SCHOFIELD, CJ
BAGGALEY, KH
CASSELS, R
机构
[1] SMITHKLINE BEECHAM PHARMACEUT,BETCHWORTH RH3 7AJ,SURREY,ENGLAND
[2] OXFORD CTR MOLEC SCI,OXFORD OX1 3QY,ENGLAND
关键词
D O I
10.1039/c39920000877
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Incubation of a gamma-lactam analogue of proclavaminic acid with clavaminic acid synthase, gave two novel bicyclic gamma-lactams.
引用
收藏
页码:877 / 879
页数:3
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