THERMODYNAMICS OF DISSOCIATION OF SOME BARBITURIC ACIDS IN AQUEOUS SOLUTION

被引：20

作者：

BRIGGS, AG

SAWBRIDG.JE

TICKLE, P

WILSON, JM

机构：

[1] Department of Chemistry, University of Technology, Loughborough, Leicestershire

来源：

JOURNAL OF THE CHEMICAL SOCIETY B-PHYSICAL ORGANIC | 1969年 / 07期

关键词：

D O I：

10.1039/j29690000802

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Values of pKa for barbituric acid and five of its alkyl and aryl derivatives have been determined spectrophotometrically at selected temperatures in the range 15-50°. From these values, ΔG°, ΔH, and ΔS° have been calculated at each temperature by use of a FORTRAN computer programme. Equations are given which enable pKa to be calculated at intermediate temperatures. The relative acid strengths are discussed in terms of inductive effects.

引用

页码：802 / &

共 16 条

[1]

ALBERT A, 1962, IONIZATION CONSTANTS, P76

[2]

BATES RG, 1954, DETERMINATION PH, P95

[3]

BELL RP, 1959, PROTON CHEMISTRY, P69

[4] THERMODYNAMIC IONIZATION CONSTANTS OF BARBITURIC ACID AND SOME OF ITS DERIVATIVES [J].