A CONCISE SYNTHESIS OF THE FREDERICAMYCIN-A DEF RING-SYSTEM - [4+2] CYCLOADDITION REACTIONS OF 1-AZA-1,3-BUTADIENES

被引：25

作者：

BOGER, DL

ZHANG, MS

机构：

[1] Department of Chemistry, Scripps Research Institute, California 92037, 10666 North Torrey Pines Road, La Jolla

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1992年 / 57卷 / 14期

关键词：

D O I：

10.1021/jo00040a044

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A concise four-step synthesis of the fredericamycin A DEF ring system is detailed based on the LUMO(diene)-controlled Diels-Alder reaction of N-sulfonyl-1-azadiene 3 for introduction of the pyridone F ring.

引用

页码：3974 / 3977

页数：4

共 31 条

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[10] DIELS-ALDER REACTIONS OF 1-AZA-1,3-BUTADIENES - ROOM-TEMPERATURE, ENDO-SELECTIVE LUMODIENE-CONTROLLED [4+2]-CYCLOADDITION REACTIONS OF N-SULFONYL-4-(ETHOXYCARBONYL)-1-AZA-1,3-BUTADIENES [J].

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