A NEW CHLORINATED PHENYLPYRROLE ANTIBIOTIC PRODUCED BY THE ANTIFUNGAL BACTERIUM PSEUDOMONAS-CEPACIA

被引:36
作者
ROITMAN, JN [1 ]
MAHONEY, NE [1 ]
JANISIEWICZ, WJ [1 ]
BENSON, M [1 ]
机构
[1] USDA ARS,APPALACHIAN FRUIT RES STN,KEARNEYSVILLE,WV 25430
关键词
D O I
10.1021/jf00092a044
中图分类号
S [农业科学];
学科分类号
09 ;
摘要
A group of chlorinated phenylpyrrole derivatives was isolated from a strain of Pseudomonas cepacia collected from apple leaves during a screening program designed to detect agents for biological control of fruit spoilage fungi. One of these substances, 2,3-dichloro-4-(2-amino-3-chlorophenyl)pyrrole, has not been previously reported. In vitro testing showed that all four of the phenylpyrroles had antifungal activity toward several fruit pathogens. The new phenylpyrrole showed fungal inhibitory effects on Golden Delicious apples inoculated with conidia of pathogenic organisms. An unrelated but known compound, 2-(2-heptenyl)-3-methyl-4(1H)-quinolone, was also isolated. © 1990, American Chemical Society. All rights reserved.
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页码:538 / 541
页数:4
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