DISCRIMINATION OF CAPILLARY AND ARTERIO-VENULAR BLOOD-FLOW IN SKIN BY LASER DOPPLER FLOWMETRY

被引:50
作者
GUSH, RJ
KING, TA
机构
[1] UNIV MANCHESTER,DEPT PHYS,MANCHESTER M13 9PL,LANCS,ENGLAND
[2] UNIV MANCHESTER,LASER RES GRP,MANCHESTER M13 9PL,LANCS,ENGLAND
关键词
AUTOCORRELATION; LASER DOPPLER FLOWMETRY; MICROVASCULAR RESPONSE; SKIN BLOOD FLOW; WAVELENGTH DEPENDENCE;
D O I
10.1007/BF02441659
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
The scattering and absorption of light by tissue and blood is wavelength dependent; the tissue penetration of green light (lambda = 543.5 nm) is about 60 per cent of that of red light (lambda = 632.8 nm) but the absorption of green light by blood is about 20 times greater than for red light. The effect of this difference has been studied by observing the responses of skin blood flow to heat and weal, measured by laser Doppler flowmetry at the two wavelengths. By using time autocorrelation function analysis (ACF) of the scattered light measured, low and high frequency components have been associated with capillary and larger vessel flow, respectively. The comparison of ACF from scattered green and red light has shown that measurements cannot be interpreted by only considering light penetration depth through a homogeneous tissue. Light absorption and multiple scattering by blood at the individual microvessel level, blood rheology and vessel morphology are parameters which are considered for greater attention.
引用
收藏
页码:387 / 392
页数:6
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