GLUCOSE-INDUCED INACTIVATION OF ISOCITRATE LYASE IN ASPERGILLUS-NIDULANS

被引：20

作者：

DELUCAS, JR

VALENCIANO, S

LABORDA, F

TURNER, G

机构：

[1] UNIV ALCALA DE HENARES, FAC FARM, DEPT MICROBIOL & PARASITOL, E-28871 ALCALA DE HENARES, SPAIN

[2] UNIV SHEFFIELD, DEPT MOLEC BIOL & BIOTECHNOL, SHEFFIELD S10 2UH, S YORKSHIRE, ENGLAND

[3] UNIV SHEFFIELD, KREBS INST BIOMOLEC RES, SHEFFIELD S10 2UH, S YORKSHIRE, ENGLAND

来源：

ARCHIVES OF MICROBIOLOGY | 1994年 / 162卷 / 06期

关键词：

ASPERGILLUS NIDULANS; CATABOLITE INACTIVATION; ISOCITRATE LYASE; CREA GENE; GENE REGULATION; FUNGI;

D O I：

10.1007/BF00282105

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The existence of a second mechanism of catabolite control of isocitrate lyase of Aspergillus nidulans, in addition to the carbon catabolite repression phenomenon recently reported was analysed. Isocitrate lyase was rapidly and specifically inactivated by glucose. The inactivation was irreversible at all stages in the presence of cycloheximide, showing that reactivation depends on de novo protein synthesis. In addition, analysis of glucose-induced inactivation of isocitrate lyase in a creA(d)-30 strain showed that the creA gene is not involved in this process.

引用

页码：409 / 413

页数：5

共 35 条

[1] AN INVERSION TRUNCATING THE CREA GENE OF ASPERGILLUS-NIDULANS RESULTS IN CARBON CATABOLITE DEREPRESSION [J].