TRANSFORMING GROWTH-FACTOR-ALPHA

被引：83

作者：

KUMAR, V ^{[1
]}

BUSTIN, SA ^{[1
]}

MCKAY, IA ^{[1
]}

机构：

[1] LONDON HOSP,COLL MED,ACAD SURG UNIT,LONDON E1 2BL,ENGLAND

来源：

CELL BIOLOGY INTERNATIONAL | 1995年 / 19卷 / 05期

关键词：

D O I：

10.1006/cbir.1995.1083

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Transforming growth factor alpha (TGF alpha) is a close relative of epidermal growth factor (EGF), the first polypeptide mitogen discovered in 1962 (Cohen, 1962). TGF alpha, like EGF, exerts its effect on cells through binding to the EGF-Receptor (EGF-R). Here we review the molecular and cell biology of TGF alpha before proceeding to describe our own work an signaling molecules induced in response to activation of the EGF-R.

引用

页码：373 / 388

页数：16

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