ASSOCIATION BETWEEN PREGNANCY-ASSOCIATED ALPHA-2-GLYCOPROTEIN (ALPHA-2-PAG) AND MIXED LEUKOCYTE REACTION DETERMINANTS ON THE LEUKOCYTE SURFACE

被引：17

作者：

HORNE, CHW ^{[1
]}

THOMSON, AW ^{[1
]}

HUNTER, CBJ ^{[1
]}

VANHEYNINGEN, V ^{[1
]}

DEANE, DL ^{[1
]}

STEEL, CM ^{[1
]}

机构：

[1] WESTERN GEN HOSP,MRC,CLIN & POPULAT CYTOGENET UNIT,EDINBURGH EH4 2XU,MIDLOTHIAN,SCOTLAND

来源：

EXPERIENTIA | 1979年 / 35卷 / 03期

关键词：

D O I：

10.1007/BF01964383

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

α2-PAG is present on the surface of mononuclear blood leucocytes and can be demonstrated predominantly on B-lymphocytes and monocytes. Pretreatment of cells with antibody to α2-PAG leads to a marked reduction in Fc-rosette formation. Competitive blocking experiments with specific antisera reveal a particularly close asociation between α2-PAG and MLR (mixed leucocyte reaction) determinants on the cell surface. These findings suggest one mechanism whereby α2-PAG may modify cell-mediated immune responses. © 1978 Birkhäuser Verlag.

引用

页码：411 / 412

页数：2

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