MUSCLE DAMAGE AND RECOVERY IN THE RABBIT TONGUE FOLLOWING PHOTODYNAMIC THERAPY WITH HEMATOPORPHYRIN DERIVATIVE

被引：11

作者：

JEFFERIS, AF ^{[1
]}

CHEVRETTON, EB ^{[1
]}

BERENBAUM, MC ^{[1
]}

机构：

[1] ST MARYS HOSP, DEPT EAR NOSE & THROAT, LONDON W2 1PG, ENGLAND

来源：

ACTA OTO-LARYNGOLOGICA | 1991年 / 111卷 / 01期

基金：

英国医学研究理事会;

关键词：

COPPER VAPOR DYE LASER; REGENERATION; SCARRING;

D O I：

10.3109/00016489109137367

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

To study the effects of photodynamic therapy on the tissues of the tongue. 20 New Zealand White rabbits were injected intravenously with haematoporphyrin derivative. Their tongues and those of 2 controls were illuminated with 100 J/cm2 of red light from a copper vapour-pumped dye laser emitting light at 625 nm. The rabbits were sacrificed at intervals between 2 days and 12 weeks following treatment. Their tongues were examined histologically. Initially there was marked damage to mucosa, muscle and blood vessels. However, this healed by a mixture of regeneration and scarring.

引用

页码：153 / 160

页数：8

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