PYRAZOLE DERIVATIVES .5. SYNTHESIS AND ANTINEOPLASTIC ACTIVITY OF 3-(2-CHLOROETHYL)-3,4-DIHYDRO-4-OXOPYRAZOLO[5,1-D]-1,2,3,5-TETRAZINE-8-CARBOXAMIDE AND RELATED-COMPOUNDS

被引：23

作者：

CHENG, CC ^{[1
]}

ELSLAGER, EF ^{[1
]}

WERBEL, LM ^{[1
]}

PRIEBE, SR ^{[1
]}

LEOPOLD, WR ^{[1
]}

机构：

[1] WARNER LAMBERT PARKE DAVIS,DIV PHARMACEUT RES,ANN ARBOR,MI 48105

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1986年 / 29卷 / 08期

关键词：

D O I：

10.1021/jm00158a041

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1544 / 1547

页数：4

共 26 条

[1] PYRAZOLES .I. SYNTHESIS OF 4-HYDROXYPYRAZOLO[3,4-D]-V-TRIAZINE A NEW ANALOG OF HYPOXANTHINE [J].

CHENG, CC ;

ROBINS, RK ;

CHENG, KC ;

LIN, DC .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1968, 57 (06) :1044-+

[2]

EGE G, 1979, TETRAHEDRON LETT, P4253

[3]

GERAN RI, 1972, CANC CHEMOTHER REP, V3, P1

[4] CLINICAL EVALUATION OF 5-(3,3-DIMETHYL-1-TRIAZENO)IMIDAZOLE-4-CARBOXAMIDE IN MALIGNANT MELANOMA AND OTHER NEOPLASMS - COMPARISON OF TWICE-WEEKLY AND DAILY ADMINISTRATION SCHEDULES [J].

GOTTLIEB, JA ;

SERPICK, AA .

ONCOLOGY, 1971, 25 (03) :225-&

[5]

HANO K, 1968, GANN, V59, P207

[6]

HOFFMAN G, 1968, CANCER CHEMOTH REP 1, V52, P715

[7]

KLINE I, 1981, CANCER CHEMOTHER REP, V55, P9

[8]

LEOPOLD WR, 1985, CANCER RES, V45, P5532

[9]

LEOPOLD WR, 1984, CANCER RES, V44, P1928

[10]

LUCE JK, 1970, CANCER CHEMOTH REP 1, V54, P119

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