SEQUENCES OF THE MEMBRANE-MODIFYING PEPTIDE ANTIBIOTIC TRICHOTOXIN-A-40

被引:66
作者
BRUCKNER, H [1 ]
KONIG, WA [1 ]
GREINER, M [1 ]
JUNG, G [1 ]
机构
[1] UNIV HAMBURG,INST ORGAN CHEM & BIOCHEM,D-2000 HAMBURG 13,FED REP GER
来源
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1979年 / 18卷 / 06期
关键词
D O I
10.1002/anie.197904761
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A possible model for nerve conduction is provided by the peptide antibiotic trichotoxin A‐40. The first complete sequence determination was accomplished once it had been recognized that the peptide can be fragmented highly selectively with anhydrous trifluoroacetic acid. The high content of aminoisobutyric acid (Aib) is remarkable. (Formula Presented.) Copyright © 1979 by Verlag Chemie, GmbH, Germany
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页码:476 / 477
页数:2
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