SPECIES-DIFFERENCE IN HYDROPEROXIDE-SCAVENGING ENZYMES WITH SPECIAL REFERENCE TO GLUTATHIONE-PEROXIDASE IN GUINEA-PIGS

被引：21

作者：

HIMENO, S

TAKEKAWA, A

IMURA, N

机构：

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY | 1993年 / 104卷 / 01期

关键词：

D O I：

10.1016/0305-0491(93)90334-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. As guinea-pigs have been reported to have a markedly low activity of glutathione peroxidase (GSH-Px), the activity of other hydroperoxide-scavenging enzymes was investigated. 2. Catalase activity in guinea-pig tissues was 2-3 times higher than that of mice or rats. 3. Approximately 90% of catalase activity was found in the soluble fraction of guinea-pig liver, suggesting a compensatory role of catalase in removing H2O2 in the cytosol of guinea-pig tissues. 4. In erythrocytes, GSH-Px activity does not differ among rodents. This may reflect the fact that GSH-Px is the sole enzyme in the removal of organic hydroperoxides in erythrocytes where glutathione S-transferase activity is barely detectable.

引用

页码：27 / 31

页数：5

共 22 条

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