Apoptosis and signal transduction: clues to a molecular mechanism

被引：113

作者：

Lee, Sooja ^{[1
]}

Christakos, Sylvia ^{[1
]}

Small, Michael B. ^{[2
]}

机构：

[1] Univ Med & Dent New Jersey, New Jersey Med Sch, Dept Biochem & Mol Biol, Newark, NJ 07103 USA

[2] Univ Med & Dent New Jersey, New Jersey Med Sch, Dept Microbiol & Mol Genet, Newark, NJ 07103 USA

来源：

CURRENT OPINION IN CELL BIOLOGY | 1993年 / 5卷 / 02期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0955-0674(93)90118-A

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Apoptosis, or programmed cell death, plays an essential role in specific cell deletion during normal embryonic and adult development in vertebrate and invertebrate species. Recent evidence suggests that signal transduction pathways governing cellular proliferation and cell cycle progression also mediate the physiological response to changes in the extracellular environment that trigger the anti-proliferative state characteristic of apoptosis.

引用

页码：286 / 291

页数：6

共 73 条

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