ONE-POT SYNTHESIS OF PYRIMIDINE-5-CARBOXALDEHYDE AND ETHYL PYRIMIDINE-5-CARBOXYLATE BY UTILIZING PYRIMIDIN-5-YL-LITHIUM

被引：23

作者：

RHO, TY

ABUH, YF

机构：

[1] Department of Medicinal Chemistry, Center for Drug Design and Development, College of Pharmacy, The University of Toledo, Toledo

来源：

SYNTHETIC COMMUNICATIONS | 1994年 / 24卷 / 02期

关键词：

D O I：

10.1080/00397919408013824

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Pyrimidine-5-carboxaldehyde was prepared in a one-pot reaction from 5-bromo-pyrimidine via metal halogen exchange. Pyrimidin-5-yl-lithium reacted with formate ester and ethyl cyanoformate, forming respectively the aldehyde and carboxy ethyl ester.

引用

页码：253 / 256

页数：4

共 6 条

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[3]

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[6]

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