Neonatal neurology, past present and future - A window on the brain

被引:3
作者
Dubowitz, LMS [1 ]
Cowan, F [1 ]
Rutherford, M [1 ]
Mercuri, E [1 ]
Pennock, J [1 ]
机构
[1] HAMMERSMITH HOSP, ROYAL POSTGRAD MED SCH, ROBERT STEINER MAGNET RESONANCE UNIT, LONDON, ENGLAND
关键词
newborn; MRI; ultrasound; brain; neurological examination;
D O I
10.1016/0387-7604(95)00007-0
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Interest in the neurology of the newborn has been largely stimulated by the new advances of imaging; CT, cranial ultrasonography and MRI which for the first time allowed diagnosis of brain lesions in the live infant which in the past could only be made by post mortem examinations, (Ultrasound in particular, as it is safe, cheap and portable has been eminantly suitable for routine use in the nurseries to study the incidence, timing and evolution of the lesions in the neonatal period, While MRI is expensive and more difficult to perform it gives superb anatomical definition and is also safe for repeated examinations, It is thus very suitable to follow the evolution of the lesions into infancy), The aim of this presentation is to illustrate how an integrated approach with the combined use of imaging and clinical evaluations lead to a better understanding of antenatal and perinatal factors which may be responsible for the production of these lesions on one hand and the impact of these lesions on later development on the other.
引用
收藏
页码:22 / 30
页数:9
相关论文
共 34 条
[1]   NEURODEVELOPMENTAL OUTCOME OF TRANSIENT NEONATAL INTRACEREBRAL ECHODENSITIES [J].
APPLETON, RE ;
LEE, REJ ;
HEY, EN .
ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION, 1990, 65 (01) :27-29
[2]  
BOUZA H, 1994, DEV MED CHILD NEUROL, V36, P951
[3]   EVOLUTION OF EARLY HEMIPLEGIC SIGNS IN FULL-TERM INFANTS WITH UNILATERAL BRAIN-LESIONS IN THE NEONATAL-PERIOD - A PROSPECTIVE-STUDY [J].
BOUZA, H ;
RUTHERFORD, M ;
ACOLET, D ;
PENNOCK, JM ;
DUBOWITZ, LMS .
NEUROPEDIATRICS, 1994, 25 (04) :201-207
[4]   PREDICTION OF OUTCOME IN CHILDREN WITH CONGENITAL HEMIPLEGIA - A MAGNETIC-RESONANCE-IMAGING STUDY [J].
BOUZA, H ;
DUBOWITZ, LMS ;
RUTHERFORD, M ;
PENNOCK, JM .
NEUROPEDIATRICS, 1994, 25 (02) :60-66
[5]  
BRAZELTON TB, 1973, CLIN DEV MED, V50
[6]   DIFFUSION-WEIGHTED IMAGING STUDIES OF CEREBRAL-ISCHEMIA IN GERBILS - POTENTIAL RELEVANCE TO ENERGY FAILURE [J].
BUSZA, AL ;
ALLEN, KL ;
KING, MD ;
VANBRUGGEN, N ;
WILLIAMS, SR ;
GADIAN, DG .
STROKE, 1992, 23 (11) :1602-1612
[7]  
COOKE RWI, 1979, LANCET, V2, P38
[8]   EARLY DETECTION OF CEREBRAL INFARCTION AND HYPOXIC-ISCHEMIC ENCEPHALOPATHY IN NEONATES USING DIFFUSION-WEIGHTED MAGNETIC-RESONANCE-IMAGING [J].
COWAN, EM ;
PENNOCK, JM ;
HANRAHAN, JD ;
MANJI, KP ;
EDWARDS, AD .
NEUROPEDIATRICS, 1994, 25 (04) :172-175
[9]  
DEVRIES LS, 1985, LANCET, V2, P137
[10]   ULTRASOUND EVOLUTION AND LATER OUTCOME OF INFANTS WITH PERIVENTRICULAR DENSITIES [J].
DEVRIES, LS ;
REGEV, R ;
PENNOCK, JM ;
WIGGLESWORTH, JS ;
DUBOWITZ, LMS .
EARLY HUMAN DEVELOPMENT, 1988, 16 (2-3) :225-233