PULMONARY TOXICITY AFTER RADIATION AND BLEOMYCIN - REVIEW

被引：77

作者：

CATANE, R ^{[1
]}

SCHWADE, JG ^{[1
]}

TURRISI, AT ^{[1
]}

WEBBER, BL ^{[1
]}

MUGGIA, FM ^{[1
]}

机构：

[1] NCI,DIV CANC TREATMENT,RADIAT ONCOL BRANCH,PROGRAM CLIN ONCOL,BETHESDA,MD 20014

来源：

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | 1979年 / 5卷 / 09期

关键词：

Bleomycin; Pulmonary toxicity; Radiotherapy;

D O I：

10.1016/0360-3016(79)90761-2

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The effects of bleomycin (BLM) and radiation on the lung are histologically similar. Animal studies have indicated additive or synergistic effects from these 2 agents. Review of the literature regarding clinical studies using BLM and irradiation indicates that the incidence of pulmonary toxicity increases when bleomycin is administered in conjunction with radiotherapy to the thorax. Of 115 patients treated simultaneously with BLM and radiation to the thorax, 22 (19%) suffered pulmonary toxicity that was fatal in 11 (10%). © 1979.

引用

页码：1513 / 1518

页数：6

共 39 条

[1]

BENNET DE, 1968, CANCER, V23, P1001

[2]

BLUM RH, 1973, CANCER, V31, P903, DOI 10.1002/1097-0142(197304)31:4<903::AID-CNCR2820310422>3.0.CO

[3]

2-N

[4]

BONADONNA G, 1977, CANCER TREAT REP, V61, P769

[5]

CHAN PYM, 1976, CANCER, V37, P2671, DOI 10.1002/1097-0142(197606)37:6<2671::AID-CNCR2820370615>3.0.CO

[6]

2-5

[7]

COMIS RL, 1977, CURRENT CHEMOTHERAPY, V2, P1135

[8]

CROOKE ST, 1976, J MED, V7, P333

[9]

DELENA M, 1972, CANCER CHEMOTH REP 1, V56, P343

[10]

Depierre A, 1976, Prog Biochem Pharmacol, V11, P195

← 1 2 3 4 →