SPECTROSCOPIC STUDIES ON ELASTIN-LIKE SYNTHETIC POLYPEPTIDES

被引：23

作者：

CASTIGLIONEMORELLI, A ^{[1
]}

SCOPA, A ^{[1
]}

TAMBURRO, AM ^{[1
]}

GUANTIERI, V ^{[1
]}

机构：

[1] UNIV PADUA,DEPT INORGAN METALLORGAN & ANALYT CHEM,I-35100 PADUA,ITALY

来源：

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 1990年 / 12卷 / 06期

关键词：

circular dichroism; Elastin; nuclear magnetic resonance; β-turn conformation;

D O I：

10.1016/0141-8130(90)90044-B

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Spectroscopic studies on synthetic polypeptides containing the unit X-G-G (X = V or L) are reported. The sequences, constituting either fragments or model of elastin, were shown to adopt type II β-turns together with an ensemble of unordered conformations. Furthermore, it was found that the stability of the β-turns was depending on the nature of the X residue, on the hydration of the chain and, in the case of the sequence G-V-G-G-L, was decreasing by increasing the length of the chain. © 1990.

引用

页码：363 / 368

页数：6

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