INHIBITION OF BOVINE PERICARDIUM CALCIFICATION - A COMPARATIVE-STUDY OF AL-3+ AND LIPID REMOVING TREATMENTS

被引：2

作者：

HERRERO, EJ

GUTIERREZ, MP

ESCUDERO, C

CASTILLOOLIVARES, JL

机构：

[1] Service of Experimental Surgery, Clínica Puerta de Hierro, Madrid

来源：

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE | 1991年 / 2卷 / 02期

关键词：

D O I：

10.1007/BF00703464

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

The biological heart prostheses present midterm and long term problems owing to the progressive deterioration and calcification of the tissue. In the attempt to study the latter problem, we have compared the effectiveness of anticalcification treatments in calf pericardium samples implanted into female Wistar rats after undergoing the following procedures: Group 1, control, treatment with glutaraldehyde; group 11, treated with 0.1 M Al3+ for 24 h; and group 111, subjected to lipid removal by chemical treatment with chloroform/methanol for 1 h. Positive results were obtained with both treatments, but the results after 60 days of implantation were more favourable with lipid removal than with Al3+ treatment.

引用

页码：86 / 88

页数：3

共 25 条

[1]

Schoen F.J., Collins J.J., Cohn L.H., Amer. J. Cardiol., 51, (1983)

[2]

Levy R.J., Schoen F.J., Sherman F.S., Nichols J., Hawley M.A., Lund S.A., Amer. J. Pathol., 122, (1986)

[3]

Levy R.J., Schoen F.J., Howard S.L., Amer J. Cardiol., 52, (1983)

[4]

Thubrikar M.J., Deck D.J., Aouad J., J. Thorac. Cardiovasc. Surg., 86, (1983)

[5]

Levy R.J., Zenker J.A., Lian J.B., J. Clin. Invest., 65, (1980)

[6]

Levy R.J., Gundberg C., Scheinman R., Atherosclerosis, 46, (1983)

[7]

Arbustini E., Jones M., Moses R., Amer. J. Cardiol., 57, (1984)

[8]

Carpentier A., Carpentier S., Ahmed A., Goussef N., Circulation, 79, (1984)

[9]

Levy R.J., Hawley M.A., Schoen F.J., Lund S.A., Piu P.Y., Circulation, 71, (1985)

[10]

Levy R.J., Wolfrum J., Schoen F.J., Lund S.A., Langer R., Science, 228, (1985)

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