LOCOMOTOR-ACTIVITY BUT NOT CONDITIONED PLACE PREFERENCE IS DIFFERENTIALLY AFFECTED BY A MODERATE DOSE OF ETHANOL ADMINISTERED TO P AND NP RATS

被引：30

作者：

SCHECHTER, MD

机构：

[1] Department of Pharmacology, Northeastern Ohio Universities College of Medicine, Rootstown

来源：

ALCOHOL | 1992年 / 9卷 / 03期

关键词：

CONDITIONED PLACE PREFERENCE; ETHANOL; P/NP RATS; SPONTANEOUS MOTOR ACTIVITY; TIME-COURSE;

D O I：

10.1016/0741-8329(92)90050-K

中图分类号：

R194 [卫生标准、卫生检查、医药管理];

学科分类号：

摘要：

The conditioned place preference (CPP) test and spontaneous motor activity were used in order to determine if ethanol-preferring (P) rats differ from ethanol nonpreferring (NP) rats after the administration of a moderate (1.0 g/kg) dose of ethanol. Results indicate that both of the selectively bred lines of rats found ethanol aversive, with little difference between the P and the NP rats. In contrast, the NP rats were shown to be more sensitive to the motor-impairing effect of ethanol.

引用

页码：185 / 188

页数：4

共 18 条

[1] FAILURE TO ESTABLISH A CONDITIONED PLACE PREFERENCE WITH ETHANOL IN RATS [J].