A sequence downstream of the initiation codon is essential for cold shock induction of cspB of Escherichia coli

被引：21

作者：

Etchegaray, JP ^{[1
]}

Inouye, M ^{[1
]}

机构：

[1] Univ Med & Dent New Jersey, Robert Wood Johnson Med Sch, Dept Biochem, Piscataway, NJ 08854 USA

来源：

JOURNAL OF BACTERIOLOGY | 1999年 / 181卷 / 18期

关键词：

D O I：

10.1128/JB.181.18.5852-5854.1999

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Cold shock induction of cspB has been shown to be primarily regulated at the mRNA level. were, we demonstrate that the induction of cspB at low temperature also requires the translational cis-acting element called the downstream box (DB). Full induction of cspB at low temperature is achieved in the presence of both the Shine-Dalgarno sequence and DB. We propose that the DR sequence functions as a translational enhancer for the biosynthesis of CspB to bypass the inhibitory effect in translation caused by cold shock.

引用

页码：5852 / 5854

页数：3

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