RAT BRACHIAL-PLEXUS AND ITS TERMINAL BRANCHES - AN EXPERIMENTAL-MODEL FOR THE STUDY OF PERIPHERAL-NERVE REGENERATION

被引:96
作者
BERTELLI, JA
TALEB, M
SAADI, A
MIRA, JC
PECOTDECHAVASSINE, M
机构
[1] Laboratoire de Neurobiologie, Groupe Regeneration des Nerfs Peripheriques et des Muscles Squelettiques, CNRS URA-1448, Universite Rene Descartes, Paris
[2] Laboratoire de Microchirurgie, Ecole de Chirurgie Des Hopitaux De, Paris
[3] Laboratoire de Biologie du Developpement, CNRS URA-1118, Universite Rene Descartes, Paris
[4] Institut des Neurosciences du CNRS, Universite P. et M. Curie, Departement de Neurobiologie des Signaux Intercellulaires, Paris
[5] Joana de Gusmao Childrens Hospital, Department of Plastic and Reconstructive Surgery, Florianopolis, Santa Catarina
关键词
D O I
10.1002/micr.1920160207
中图分类号
R61 [外科手术学];
学科分类号
摘要
Despite the introduction of microsurgical techniques into clinical practice, the results of surgical procedures involving the brachial plexus and peripheral nerves are still far from spectacular, We therefore studied the rat brachial plexus and its terminal branches in 203 rats, Detailed anatomic and morphologic analyses of the biceps brachii and musculocutaneous nerve, finger flexors, flexor carpi radialis, and the median nerve were performed, Various sources of conventional and vascularized nerve grafts were explored, After musculocutaneous nerve section or median nerve section, there were no articular contractures or automutilations, which constitutes an advantage for these experimental models over the sciatic nerve model, The brachial plexus and its terminal branches provide a good experimental model which can be used to assess the development and normal control of muscle function, examine the mechanisms underlying functional recovery, and test the effects of treatments to enhance recovery. (C) 1995 Wiley-Liss, Inc.
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页码:77 / 85
页数:9
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