SIMULTANEOUS DETERMINATION OF METHAQUALONE AND DIAZEPAM IN PLASMA BY DERIVATIVE SPECTROSCOPY

被引:3
作者
CRUZ, A
BERMEJO, A
LOPEZRIVADULLA, M
FERNANDEZ, P
机构
[1] Department of Legal Medicine, Forensic Toxicology Service, Faculty of Medicine, San Francisco s/n
关键词
METHAQUALONE; DIAZEPAM; DERIVATIVE SPECTROSCOPY; PLASMA DETERMINATION;
D O I
10.1080/00032719208018524
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
A spectrophotometric method for the simultaneous determination of methaqualone and diazepam in plasma by second-derivative spectroscopy is reported. The proposed method is quite sensitive (it allows the determination of therapeutic levels of both pharmaceuticals) and easy to implement. It provided average recoveries of 93.75% and 99.04% for methaqualone and diazepam, respectively.
引用
收藏
页码:253 / 268
页数:16
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