SIMULTANEOUS DETERMINATION OF METHAQUALONE AND DIAZEPAM IN PLASMA BY DERIVATIVE SPECTROSCOPY

被引：3

作者：

CRUZ, A

BERMEJO, A

LOPEZRIVADULLA, M

FERNANDEZ, P

机构：

[1] Department of Legal Medicine, Forensic Toxicology Service, Faculty of Medicine, San Francisco s/n

来源：

ANALYTICAL LETTERS | 1992年 / 25卷 / 02期

关键词：

METHAQUALONE; DIAZEPAM; DERIVATIVE SPECTROSCOPY; PLASMA DETERMINATION;

D O I：

10.1080/00032719208018524

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A spectrophotometric method for the simultaneous determination of methaqualone and diazepam in plasma by second-derivative spectroscopy is reported. The proposed method is quite sensitive (it allows the determination of therapeutic levels of both pharmaceuticals) and easy to implement. It provided average recoveries of 93.75% and 99.04% for methaqualone and diazepam, respectively.

引用

页码：253 / 268

页数：16

共 10 条

[1] APPLICATION OF DERIVATIVE SPECTROSCOPY TO THE DETERMINATION OF PLASMA THEOPHYLLINE IN THE PRESENCE OF PHENOBARBITAL [J].