CHYMOTRYPSIN-CATALYZED REACTIONS OF PHENYL HIPPURATE WITH ALCOHOLS - KINETIC EVIDENCE FOR A BINDING-SITE FOR NUCLEOPHILES

被引：12

作者：

WERBER, MM

GREENZAID, P

机构：

[1] TEL AVIV UNIV, DEPT CHEM, RAMAT AVIV, ISRAEL

[2] TEL AVIV UNIV, DEPT BIOCHEM, RAMAT AVIV, ISRAEL

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1973年 / 293卷 / 01期

关键词：

D O I：

10.1016/0005-2744(73)90393-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：208 / 216

页数：9

共 13 条

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[2] KINETICS OF ALPHA-CHYMOTRYPSIN REACTIONS IN PRESENCE OF ADDED NUCLEOPHILES [J].

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GUNTER, CR ;

KEZDY, FJ ;

CLEMENT, GE .

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[3] EFFECT OF APROTIC DIPOLAR ORGANIC SOLVENTS ON KINETICS OF ALPHA-CHYMOTRYPSIN-CATALYZED HYDROLYSES [J].

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BENDER, ML .

BIOCHEMISTRY, 1963, 2 (04) :836-&

[4] BINDING SITES FOR SUBSTRATE LEAVING GROUPS AND ADDED NUCLEOPHILES IN PAPAIN-CATALYZED HYDROLYSES [J].

FINK, AL ;

BENDER, ML .

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[5]

GREENZAI.P, 1971, BIOCHEMISTRY-US, V10, P1210

[6]

HINKLE PM, 1971, BIOCHEMISTRY-US, V10, P2717

[7]

INWARD PW, 1965, J BIOL CHEM, V240, P1986

[8] ORIENTATION EFFECTS IN REACTIONS OF ACYL CHYMOTRYPSINS [J].

OLEARY, MH ;

KLUETZ, MD .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1971, 93 (26) :7341-&

[9] NUCLEOPHILIC COMPETITION IN ENZYME HYDROLSIS REACTIONS - KINETIC ANALYSIS AND APPLICATION TO TRYPSIN HYDROLYSIS OF SOME ESTERS [J].

SEYDOUX, F ;

YON, J .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1967, 3 (01) :42-&

[10]

WEISS F, 1893, BER DEUT CHEM GES, V26, P1700

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