PROGNOSTIC FACTORS IN MALIGNANT GLIOMAS WITH SPECIAL REFERENCE TO INTRAARTERIAL CHEMOTHERAPY

被引：23

作者：

WATNE, K

HANNISDAL, E

NOME, O

HAGER, B

HIRSCHBERG, H

机构：

[1] NORWEGIAN RADIUM HOSP, DEPT ONCOL, OSLO 3, NORWAY

[2] NORWEGIAN RADIUM HOSP, DEPT RADIOL, OSLO 3, NORWAY

来源：

ACTA ONCOLOGICA | 1993年 / 32卷 / 03期

关键词：

D O I：

10.3109/02841869309093600

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Survival was analyzed in 173 patients with malignant gliomas to study the importance of possible pretreatment prognostic factors. Seventy-nine of these patients received preirradiation intra-arterial chemotherapy with BCNU combined with vincristine intravenously and procarbazine orally; the others received only postoperative whole-brain irradiation. To judge by univariate and multivariate analyses the most important pretreatment prognostic factors were histology, corticosteroid dependency, pretreatment performance status and frontal lobe location of the tumors. Patients with anaplastic astrocytoma, not corticosteroid-dependent, with pretreatment performance status of 0-2 and with a frontal lobe location of the tumor seemed to benefit most from preirradiation chemotherapy.

引用

页码：307 / 310

页数：4

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