THE ANEMIA OF ACUTE-RENAL-FAILURE - ASSOCIATION WITH OLIGURIA AND ELEVATED BLOOD UREA

被引：17

作者：

HALES, M ^{[1
]}

SOLEZ, K ^{[1
]}

KJELLSTRAND, C ^{[1
]}

机构：

[1] UNIV ALBERTA,FAC MED,DEPT LAB MED & PATHOL,EDMONTON,AB,CANADA

来源：

RENAL FAILURE | 1994年 / 16卷 / 01期

关键词：

D O I：

10.3109/08860229409044854

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Anemia is very frequent in patients with acute failure but the nature of the relationship between the two conditions has remained unclear. We studied all patients with well-documented acute renal failure seen in consultation by our nephrology division during 1991. Fifty-three of the 56 patients had at least mild anemia (hematocrit < 35%) at some point during their hospital stay. Forty-three of the patients had a hematocrit below 30% and 14 had a hematocrit below this level on admission. Twenty-four of the patients underwent major operations and all of these patients required blood transfusions. In this group there was a significant correlation between maximum serum urea and lowest hemoglobin (r = 0.4, p <.05) but no similar correlation between maximum creatinine and lowest hemoglobin. Oliguric patients had a mean lowest hemoglobin of 7.3 +/- 0.4 g/dL, which was significantly lower than the value for nonoliguric patients, 9.0 +/- 0.4 g/dL. This study confirms the presence of anemia in 91% of patients with acute renal failure and shows it to be related to rise in urea and presence of oliguria. Clearly, however, the anemia is multifactorial, since in one-quarter of the patients it precedes onset of renal failure.

引用

页码：125 / 131

页数：7

共 16 条

[1]

Esbach W.E., Adamson J.W., Anemia in renal disease, Diseuses of the Kidney4th ed, pp. 3019-3034, (1988)

[2]

Steinman T.I., Lazarus J.M., Organ-system involvement in acute renal failure, Acute Renal Failure2nd ed, pp. 705-739, (1988)

[3]

Swan R.C., Merrill J.P., The clinical course of acute renal failure, Medicine, 32, pp. 215-292, (1953)

[4]

Minuth A.N., Terriell J.B., Suki W.N., Acute renal failure: a study of the course and prognosis of 104 patients and the role of furosemide, Am J Med Sci, 271, (1976)

[5]

Teschan P.E., Barter C.R., Prophylactic hemodialysis in the treatment of acute renal failure, Ann Int Med, 53, (1960)

[6]

Easterling R.E., Forland M., A five year experience with prophylactic dialysis for acute renal failure, Trans Am Soc Artif lntern Organs, 10, (1964)

[7]

Nielsen O.J., Thaysen J.H., Erythropoietin deficiency in acute renal failure, Lancet, 1, pp. 624-625, (1989)

[8]

Lipkin G.W., Kendall R., Haggett P., Turney J.H., Brownjohn A.M., Erythropoietin in acute renal failure, Lancet, 1, (1989)

[9]

Nielsen O.J., Thaysen J.H., Erythropoietin deficiency in acute tubular necrosis, J Int Med, 227, pp. 373-380, (1990)

[10]

Vaziri N.D., Zhou X.J., Enhances recovery from cisplatin (CP) induced acute renal failure (ARF) by recombinant erythropoietin (REPO) administration, JASN, 2, (1991)

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