REVERSAL OF THE ANTI-IMPLANTATIONAL EFFECT OF LUTEINIZING-HORMONE-RELEASING HORMONE (LRH) BY ESTRADIOL-17-BETA AND PROGESTERONE, ALONE AND IN SEQUENCE

被引:4
作者
JONES, RC
机构
[1] Endocrinology Section, Research Division, Wyeth Laboratories, Inc., Philadelphia, PA 19101
关键词
D O I
10.1016/0010-7824(79)90018-0
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
The use of estradiol-17β and progesterone, alone or in sequence, to reverse the anti-implantational effect of 100 and 500 μg LRH has been studied. Sequential administration of the steroids was most efficacious in reversing the effect of 100 μg while progesterone alone proved to be the only treatment inhibiting the effect of 500 μg LRH. A possible difference in mechanism of action of the two doses of LRH is discussed. © 1979.
引用
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页码:239 / 245
页数:7
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