SYNTHESIS AND PROPERTIES OF A BILIRUBIN ANALOG WITH PROPIONIC-ACID GROUPS REPLACED BY CARBOXYL

被引：17

作者：

BYUN, YS

LIGHTNER, DA

机构：

[1] Department of Chemistry, University of Nevada, Reno, Nevada

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1991年 / 28卷 / 07期

关键词：

D O I：

10.1002/jhet.5570280707

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The unnatural bile pigment analog of bilirubin-IX-alpha, 2,3,7,13,17,18-hexamethyl-(10H,21H,23H,24H)-bilin-1,19-dione-8,12-dicarboxylic acid (1), was synthesized as its diethyl ester by coupling 4,4'-dimethyl-3,3'-dicarboethoxydipyrrylmethane-5,5'dialdehyde with 3,4-dimethylpyrrolin-2-one.

引用

页码：1683 / 1692

页数：10

共 19 条

[1]

DEGROOT JA, 1982, THESIS U LEIDEN, P82

[2]

Falk H., 1989, CHEM LINEAR OLIGOPYR

[3]

FISCHER H, 1934, CHEM PYRROLS, V1, P255

[4] SULFOXIDES AS CHIRAL COMPLEXATION AGENTS - CONFORMATIONAL ENANTIOMER RESOLUTION AND INDUCED CIRCULAR-DICHROISM OF BILIRUBINS [J].