A COMPARATIVE BURN WOUND MODEL IN THE NEW YORKSHIRE PIG FOR THE HISTOPATHOLOGICAL EVALUATION OF LOCAL THERAPEUTIC REGIMENS - SILVER SULFADIAZINE CREAM AS A STANDARD

被引：60

作者：

HOEKSTRA, MJ

HUPKENS, P

DUTRIEUX, RP

BOSCH, MMC

BRANS, TA

KREIS, RW

机构：

[1] LEIDEN CYTOL & PATHOL LAB, LEIDEN, NETHERLANDS

[2] DUTCH BURNS FDN, BEVERWIJK, NETHERLANDS

[3] ACAD HOSP UTRECHT, DEPT PATHOL, UTRECHT, NETHERLANDS

来源：

BRITISH JOURNAL OF PLASTIC SURGERY | 1993年 / 46卷 / 07期

关键词：

D O I：

10.1016/0007-1226(93)90111-N

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

A standard burn wound model was developed in the pig to enable evaluation of histopathological parameters of wound healing under different circumstances. Wounds on one flank were treated with silver sulfadiazine 1% cream (SSD, Flammazine-Duphar), which is a standard treatment. On identical places of the contralateral side different topical agents were applied. From the SSD treated burns a typical histopathologic picture of wound heating under SSD could be derived: SSD has the potential to preserve viable dermal tissue, epidermal regeneration is rather slow and irritated, while the formation of granulation tissue is pronounced, with an abundance of myofibroblasts.

引用

页码：585 / 589

页数：5

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