HOST AGE AS A DETERMINANT OF NATURALLY ACQUIRED-IMMUNITY TO PLASMODIUM-FALCIPARUM

被引：212

作者：

BAIRD, JK

机构：

来源：

PARASITOLOGY TODAY | 1995年 / 11卷 / 03期

关键词：

D O I：

10.1016/0169-4758(95)80167-7

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

The usual course of infection by Plasmodium falciparum among adults who lack a history of exposure to endemic malaria is fulminant. The infection in adults living with hyper- to holoendemic malaria is chronic and benign. Naturally acquired immunity to falciparum malaria is the basis of this difference. Confusion surrounds an essential question regarding this process: What is its rate of onset? Opinions vary because of disagreement over the relationships between exposure to infection, antigenic polymorphism and naturally acquired immunity. In this review, Kevin Baird discusses these relationships against a backdrop of host age as a determinant of naturally acquired immunity to falciparum malaria.

引用

页码：105 / 111

页数：7

共 66 条

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