The probability of pregnancy after embryo transfer is affected by the age of the patient, cause of infertility, number of embryos transferred and the average morphology score, as revealed by multiple logistic regression analysis

被引:122
作者
Roseboom, TJ [1 ]
Vermeiden, JPW [1 ]
Schoute, E [1 ]
Lens, JW [1 ]
Schats, R [1 ]
机构
[1] FREE UNIV AMSTERDAM HOSP,DEPT REPROD ENDOCRINOL,CTR IVF,AMSTERDAM,NETHERLANDS
关键词
embryo morphology; IVF; multiple logistic regression analysis; probability of pregnancy;
D O I
10.1093/oxfordjournals.humrep.a135842
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Because the process of conception is affected by many variables, a multiple logistic regression analysis was performed to assess (i) the impact and relative weight of both patient and embryo variables and (ii) their possible effects on the probability of a vital pregnancy after embryo transfer, A statistical model was constructed predicting the probability of pregnancy after embryo transfer, The variables that contributed significantly to the predictive value of the model were the age of the patient, the cause of infertility, the number of embryos transferred and the average morphology score of the transferred embryos, Embryo variables appeared to have a significant but modest value in predicting the probability of pregnancy after embryo transfer, Other variables, such as the thickness of the endometrium, were found to have no prognostic value, Moreover, we found that their effect could be explained by the variables already included in the model.
引用
收藏
页码:3035 / 3041
页数:7
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