Targeted radiotherapy, using systemically administered radionuclides, is an exciting proposition for the treatment of disseminated disease. In neuroblastoma, two groups of compounds have been developed as radiation delivery systems: monoclonal antibodies, exemplified by UJ13A, and the small‐molecular‐weight radio‐pharmaceutical meta‐Iodobenzylguanidene (mIBG). Copyright © 1990 Wiley‐Liss, Inc., A Wiley Company