SIMPLE APPROACH TO 1-AZASPIRO[4.5]DECANES

被引：19

作者：

DUHAMEL, L ^{[1
]}

POIRIER, JM ^{[1
]}

GRANGER, P ^{[1
]}

机构：

[1] UNIV ROUEN,SERV COMMUN RMN,F-76130 MT ST AIGNAN,FRANCE

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1979年 / 44卷 / 20期

关键词：

D O I：

10.1021/jo01334a029

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1-Aza[n.5]spiranes have recently attracted considerable attention because they are present in various natural products such as the cephalotaxus alkaloids2 and his-trionicotoxine groups.3 We now report a novel route to spiro heterocyclic compounds in a one-pot reaction from enamines and their α-bromo iminium salts. © 1979, American Chemical Society. All rights reserved.

引用

页码：3576 / 3578

页数：3

共 19 条

[1]

BUZAS A, 1977, HETEROCYCLES, V6, P1037

[2]

CHUPP JP, 1967, J ORG CHEM, V32, P3246

[3]

COSTA C, 1977, TETRAHEDRON, P315

[4] HISTRIONICOTOXINS - ROENTGEN-RAY ANALYSIS OF NOVEL ALLENIC AND ACETYLENIC SPIROALKALOIDS ISOLATED FROM A COLOMBIAN FROG, DENDROBATES-HISRIONICUS [J].

DALY, JW ;

KARLE, I ;

MYERS, CW ;

TOKUYAMA, T ;

WATERS, JA ;

WITKOP, B .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1971, 68 (08) :1870-&

[5]

DUHAMEL L, 1972, TETRAHEDRON LETT, P4743

[6]

DUHAMEL L, 1976, TETRAHEDRON LETT, P2437

[7]

DUHAMEL L, 1973, TETRAHEDRON LETT, P4237

[8]

DUHAMEL P, 1971, CR ACAD SCI C CHIM, V273, P1461

[9]

Evans D.A., 1970, J AM CHEM SOC, V92, P7593

[10]

EVANS DA, 1974, ORG SYNTH, V54, P93

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