EFFECT OF APOMORPHINE ON PENILE TUMESCENCE IN MEN WITH PSYCHOGENIC IMPOTENCE

被引：56

作者：

SEGRAVES, RT

BARI, M

SEGRAVES, K

SPIRNAK, P

机构：

[1] CASE WESTERN RESERVE UNIV,DEPT PSYCHIAT,CLEVELAND,OH 44106

[2] CASE WESTERN RESERVE UNIV,DEPT UROL,CLEVELAND,OH 44106

来源：

JOURNAL OF UROLOGY | 1991年 / 145卷 / 06期

关键词：

APOMORPHINE; PENILE ERECTION; IMPOTENCE; PENIS;

D O I：

10.1016/S0022-5347(17)38565-8

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

In a double-blind study using physiological recording of penile tumescence, brachial subcutaneous apomorphine hydrochloride injections elicited penile erections in men with psychogenic impotence. This observation is compatible with the hypothesis of central dopaminergic involvement in human penile erection. Since apomorphine is believed to induce erections by its effect on brain monoamine pathways, apomorphine response may have diagnostic use in evaluating the etiology of erectile failure.

引用

收藏

页码：1174 / 1175

页数：2

相关论文

共 10 条

[1] ASSESSMENT OF ERECTOGENIC PROPERTIES OF APOMORPHINE AND YOHIMBINE IN MAN [J].

DANJOU, P ;

ALEXANDRE, L ;

WAROT, D ;

LACOMBLEZ, L ;

PUECH, AJ .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1988, 26 (06) :733-739

[2] EFFECTS OF D2-DOPAMINERGIC RECEPTOR STIMULATION ON MALE-RAT SEXUAL-BEHAVIOR [J].

FOREMAN, MM ;

HALL, JL .

JOURNAL OF NEURAL TRANSMISSION, 1987, 68 (3-4) :153-170

[3] EFFECT OF APOMORPHINE, A DOPAMINE RECEPTOR AGONIST, ON PENILE TUMESCENCE IN NORMAL SUBJECTS [J].

LAL, S ;

ACKMAN, D ;

THAVUNDAYIL, JX ;

KIELY, ME ;

ETIENNE, P .

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 1984, 8 (4-6) :695-699

[4] APOMORPHINE-INDUCED PENILE TUMESCENCE IN IMPOTENT PATIENTS - PRELIMINARY FINDINGS [J].

LAL, S ;

LARYEA, E ;

THAVUNDAYIL, JX ;

NAIR, NPV ;

NEGRETE, J ;

ACKMAN, D ;

BLUNDELL, P ;

GARDINER, RJ .

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 1987, 11 (2-3) :235-242

[5] EFFECT OF NALOXONE OR LEVALLORPHAN ON SERUM PROLACTIN CONCENTRATIONS AND APOMORPHINE-INDUCED GROWTH-HORMONE SECRETION [J].

LAL, S ;

NAIR, NPV ;

CERVANTES, P ;

PULMAN, J ;

GUYDA, H .

ACTA PSYCHIATRICA SCANDINAVICA, 1979, 59 (02) :173-179

[6] EFFECT OF DOMPERIDONE ON APOMORPHINE-INDUCED GROWTH-HORMONE SECRETION IN NORMAL MEN [J].

LAL, S ;

NAIR, NPV ;

ISKANDAR, HL ;

ETIENNE, P ;

WOOD, PL ;

SCHWARTZ, G ;

GUYDA, H .

JOURNAL OF NEURAL TRANSMISSION, 1982, 54 (1-2) :75-84

[7] EFFECT OF METHYSERGIDE AND PIMOZIDE ON APOMORPHINE-INDUCED GROWTH-HORMONE SECRETION IN MEN [J].

LAL, S ;

GUYDA, H ;

BIKADOROFF, S .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1977, 44 (04) :766-770

[8] APOMORPHINE - CLINICAL-STUDIES ON ERECTILE IMPOTENCE AND YAWNING [J].

LAL, S ;

TESFAYE, Y ;

THAVUNDAYIL, JX ;

THOMPSON, TR ;

KIELY, ME ;

NAIR, NPV ;

GRASSINO, A ;

DUBROVSKY, B .

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 1989, 13 (3-4) :329-339

[9] USE OF SEXUAL HISTORY TO DIFFERENTIATE ORGANIC FROM PSYCHOGENIC IMPOTENCE [J].

SEGRAVES, KA ;

SEGRAVES, RT ;

SCHOENBERG, HW .

ARCHIVES OF SEXUAL BEHAVIOR, 1987, 16 (02) :125-137

[10]

SEGRAVES RT, 1989, ARCH GEN PSYCHIAT, V46, P275