ESTROGEN PRODUCTION BY FETAL AND INFANTILE RAT OVARIES

被引：29

作者：

WENIGER, JP

ZEIS, A

CHOURAQUI, J

机构：

[1] Université Louis-Pasteur, Laboratoire de Zoologie et d'Embryologie Expérimentale, Strasbourg

来源：

REPRODUCTION NUTRITION DEVELOPMENT | 1993年 / 33卷 / 02期

关键词：

ESTRONE; ESTRADIOL; GONADOTROPIN; FETAL RAT OVARY;

D O I：

10.1051/rnd:19930205

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The de novo production of estrone and estradiol by the fetal and infantile rat ovary and its regulation by cAMP, LH and FSH were investigated. Basal estrogen secretion was not demonstrable before d 5 after birth. However, the fetal ovary was responsive to cAMP as early as 14 d old. Estrone was the main estrogen secreted. Steroid aromatase inhibitors inhibited cAMP-stimulated estrone secretion. Responsiveness to LH and FSH appeared at 5 d after birth. The proportion of estradiol grew more important with advancing age, becoming predominant at 7 d.

引用

页码：129 / 136

页数：8

共 30 条

[1]

[Anonymous], ARCH ANAT MICR MORPH

[2]

BENHAIM A, 1983, CR ACAD SCI III-VIE, V297, P247

[3] PITUITARY AND PLASMA-LEVELS OF GONADOTROPINS IN FETAL AND NEWBORN MALE AND FEMALE RATS [J].