SENSITIVITY TO SENSITINS AND TUBERCULIN IN SWEDISH CHILDREN .5. A STUDY OF SCHOOL-CHILDREN IN AN INLAND RURAL AREA

被引:29
作者
LARSSON, LO
BENTZON, MW
LIND, A
MAGNUSSON, M
SANDEGARD, G
SKOOGH, BE
BOETHIUS, G
机构
[1] UNIV GOTEBORG,DEPT PULM MED,GOTHENBURG,SWEDEN
[2] STATENS SERUM INST,COPENHAGEN,DENMARK
[3] UNIV GOTEBORG,DEPT MED MICROBIOL & IMMUNOL,GOTHENBURG,SWEDEN
[4] DEPT PULM MED,OSTERSUND,SWEDEN
[5] SCH HLTH SERV,OSTERSUND,SWEDEN
来源
TUBERCLE AND LUNG DISEASE | 1993年 / 74卷 / 06期
关键词
D O I
10.1016/0962-8479(93)90079-D
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Setting: Since 1986 we have tested approximately 7000 non-BCG-vaccinated Swedish children with tuberculin and with Mycobacterium avium or M. scrofulaceum sensitin. In Goteborg, an urban coastal area, 25% of 8-9-year-old school children reacted to M. avium sensitin and 32% of M. scrofulaceum sensitin using a 6 mm cut-off. Objective: To evaluate if geographical factors have an influence on the prevalence of children reacting to tuberculin and sensitins. Design: 2000 schoolchildren of the same age as those in Goteborg but living in an inland rural area were Mantoux-tested in a similar way (simultaneously on separate arms with PPD RT23 and either of the two sensitins). Results: 15% reacted to PPD RT23, 9.7% to M. avium and 13.9% to M. scrofulaceum sensitin. None of the children with a pro RT23 reaction >=6 mm showed signs of tuberculosis or had any known exposure. A reaction to PPD RT23 was usually combined with a still larger sensitin reaction. Conclusion: There was a considerable geographic difference in sensitin reactivity, low in an inland rural area compared to a coastal urban area. Children reacting to PPD RT23 had probably not been infected by M. tuberculosis but more likely by atypical mycobacteria. The reactions should be interpreted as cross-reactions.
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页码:371 / 376
页数:6
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