A COMPARATIVE STUDY ON PHOSPHOGLYCERIC ACID CYCLE IN MAMMALIAN ERYTHROCYTES

被引:47
作者
HARKNESS, DR
PONCE, J
GRAYSON, V
机构
[1] Department of Medicine, University of Miami School of Medicine, Miami, FL
来源
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY | 1969年 / 28卷 / 01期
基金
美国国家卫生研究院;
关键词
D O I
10.1016/0010-406X(69)91327-9
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
1. 1. The activities of the enzymes and intracellular concentrations of substrates and cofactors associated with phosphoglyceric acid metabolism in erythrocytes of nine mammals are reported. 2. 2. In every case 2,3-DPG phosphatase activity was lower than that of the other enzymes measured: glyceraldehyde phosphate dehydrogenase, diphosphoglycerate mutase, phosphoglycerate kinase and phosphoglycerate mutase. 3. 3. The red blood cells of man, rabbit, dolphin and pig contain high concentrations of 2,3-DPG and ATP whereas bovine, caprine and feline erythrocytes contain little of either compound. Equine erythrocytes contain large amounts of 2,3-DPG but little ATP. 4. 4. No 2,3-DPG and only very small amounts of diphosphoglyceric acid mutase was detected in the erythrocytes of the goat. © 1969.
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页码:129 / &
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