CARCINOGENIC EFFECTS OF DI(2-HYDROXYPROPYL)NITROSAMINE (DHPN) IN MALE WISTAR RATS - PROMOTION OF PANCREATIC-CANCER BY A RAW SOYA FLOUR DIET

被引：62

作者：

LEVISON, DA

MORGAN, RGH

BRIMACOMBE, JS

HOPWOOD, D

COGHILL, G

WORMSLEY, KG

机构：

[1] UNIV DUNDEE,DEPT PATHOL,DUNDEE DD1 4HN,SCOTLAND

[2] UNIV DUNDEE,DEPT CHEM,DUNDEE DD1 4HN,SCOTLAND

[3] UNIV DUNDEE,DEPT THERAPEUT,DUNDEE DD1 4HN,SCOTLAND

来源：

SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY | 1979年 / 14卷 / 02期

关键词：

Nitrosamine; Pancreatic cancer; Soya flour;

D O I：

10.3109/00365527909179873

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Di(2-hydroxypropyl)nitrosamine was administered to rats fed raw or heated (control) soya flour diets. The group fed raw soya flour developed hyperplastic and adenomatous pancreatic nodules and pancreatic adenocarcinomata. We conclude that a diet of raw soya flour augments the carcinogenicity of pancreatic carcinogens in the rat. © 1979 Informa UK Ltd.

引用

页码：217 / 224

页数：8

共 19 条

[1]

ALTHOFF J, 1977, Z KREBSFORSCH KLIN O, V90, P127

[2] CANCER OF STOMACH AND PANCREAS IN GUINEA-PIGS INDUCED BY METHYLNITROSO-UREA AND -URETHANE [J].