COMPLETE NUCLEOTIDE-SEQUENCE OF THE GROUP-I RNA BACTERIOPHAGE FR

被引：23

作者：

ADHIN, MR

AVOTS, A

BERZIN, V

OVERBEEK, GP

VANDUIN, J

机构：

[1] LEIDEN STATE UNIV,GORLAEUS LABS,DEPT BIOCHEM,POB 9502,2300 RA LEIDEN,NETHERLANDS

[2] ACAD SCI LASSR,INST ORGAN SYNTH,RIGA 226006,LATVIA,USSR

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1990年 / 1050卷 / 1-3期

关键词：

RNA phage; Sequence comparison;

D O I：

10.1016/0167-4781(90)90149-V

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We report the complete nucleotide sequence of the group I RNA bacteriophage fr. The entire genome consists of 3575 nucleotides, six nucleotides more than the only other sequenced group I representative, MS2. The greatest divergence between these phages occurs in the 5′ terminal region of the A gene, while the lysis-replicase gene overlap, the coat gene and the central region of the replicase gene are highly conserved. Overall sequence homology between fr and MS2 is 77%. Here, we present a general comparison between the two phages. In the accompanying paper we use phylogenetic sequence comparison between MS2 and fr to deduce the secondary structure at the 3′ untranslated region. © 1990.

引用

页码：104 / 109

页数：6

共 24 条

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